#6: University of Pennsylvania – Pennsylvania
The University of Pennsylvania stands out as the state’s toughest entry, with only 8% acceptance. Candidates need SAT scores between 1460-1570 or ACT scores of 33-35. Its prestige and stringent requirements place it in Pennsylvania’s top 10.

Famed for its business college, the University of Pennsylvania shines brightest here, boasting a #1 ranking. It also excels in finance, accounting, and nursing, maintaining high rankings in these disciplines.